The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2017

Filed:

May. 05, 2010
Applicants:

Thomas E. Tarara, San Diego, CA (US);

Jeffrey G. Weers, San Diego, CA (US);

Alexey Kabalnov, Corvallis, OR (US);

Ernest G. Schutt, San Diego, CA (US);

Luis A. Dellamary, San Marcos, CA (US);

Inventors:

Thomas E. Tarara, San Diego, CA (US);

Jeffrey G. Weers, San Diego, CA (US);

Alexey Kabalnov, Corvallis, OR (US);

Ernest G. Schutt, San Diego, CA (US);

Luis A. Dellamary, San Marcos, CA (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 31/685 (2006.01);
U.S. Cl.
CPC ...
A61K 9/008 (2013.01); A61K 9/0073 (2013.01); A61K 9/0075 (2013.01); A61K 9/0078 (2013.01); A61K 9/1611 (2013.01); A61K 9/1617 (2013.01); A61K 9/1641 (2013.01); A61K 9/1652 (2013.01); A61K 9/1694 (2013.01); A61K 31/685 (2013.01); A61K 9/1635 (2013.01); Y10S 514/937 (2013.01); Y10S 977/904 (2013.01); Y10S 977/906 (2013.01); Y10S 977/926 (2013.01);
Abstract

A pulmonary delivery medicament comprises a plurality of particulates, the particulates comprising a structural matrix and a water insoluble and/or crystalline active agent. The particulates have a geometric diameter of 0.5 to 50 μm. The water insoluble active agent can be a fungicide, antibiotic, budesonide. A method of making the medicament comprises forming a liquid feedstock, and forming a feedstock suspension by suspending in the liquid feedstock, the active agent and an excipient capable of forming a structural matrix, such as a phospholipid. The feedstock suspension is spray dried to produce the particulates.


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