The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2017
Filed:
Feb. 17, 2010
Sylvain Cormier, Mendon, MA (US);
Richard W. Andrews, Rehoboth, MA (US);
Robert Tacconi, Medfield, MA (US);
Craig H. Dobbs, Mendon, MA (US);
Sylvain Cormier, Mendon, MA (US);
Richard W. Andrews, Rehoboth, MA (US);
Robert Tacconi, Medfield, MA (US);
Craig H. Dobbs, Mendon, MA (US);
Waters Technologies Corporation, Milford, MA (US);
Abstract
Described are a method and system for diluting a sample in a liquid chromatography system. A sample flowing at a first flow rate is combined for a predetermined time with a diluent flowing at a second flow rate to generate a volume of diluted sample. The diluted sample has a dilution ratio determined according to the two flow rates. A portion of the volume is loaded into a sample loop of an injection valve and subsequently injected into a mobile phase flowing to a chromatography column. The method eliminates the need to have a technician available to perform dilutions or to transfer the sample to a remote location for dilution. Advantageously, manufacturing or processing downtime to perform the dilution is not required and the amount of sample flowing to waste is reduced.