The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2017

Filed:

Jun. 17, 2013
Applicant:

Pacific Biosciences of California, Inc., Menlo Park, CA (US);

Inventors:

Stephen Turner, Menlo Park, CA (US);

Mark McDonald, Milpitas, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); C12M 1/34 (2006.01); C12Q 1/68 (2006.01); G01N 21/64 (2006.01); G09G 5/00 (2006.01); G02F 1/1335 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); G01N 21/648 (2013.01); G01N 21/6428 (2013.01); G01N 21/6454 (2013.01); B01L 3/502715 (2013.01); G01N 2021/6421 (2013.01); G01N 2021/6441 (2013.01); G01N 2021/6463 (2013.01); G01N 2021/6471 (2013.01); G01N 2021/6482 (2013.01); G01N 2021/6484 (2013.01);
Abstract

An approach to the design of the set of filters which allows for the collection of a larger portion of the optical signal while still distinguishing the presence of the various fluorophores is described. In some embodiments, the filter sets of the invention each block a smaller portion of the spectrum, allowing for a larger portion of the emitted light to be detected. The combined information from the light passing through two or more of the filters is then used to determine the presence of a given fluorophore. The filter sets of the invention can be particularly useful in integrated devices in which the light from a single molecule reaction in a small reaction region is directed to a detector or to a specific portion of a detector.


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