The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2017

Filed:

Jan. 22, 2015
Applicant:

Ibio, Inc., Newark, DE (US);

Inventors:

Oleg Fedorkin, Newark, DE (US);

Shailaja Rabindran, Newark, DE (US);

Vidadi Yusibov, Havertown, PA (US);

Assignee:

iBio, Inc., Newark, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C07K 14/61 (2006.01); C07K 14/62 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8203 (2013.01); C07K 14/61 (2013.01); C07K 14/62 (2013.01); C12N 15/8257 (2013.01);
Abstract

The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.


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