The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2017

Filed:

Jul. 18, 2014
Applicant:

Butamax Advanced Biofuels Llc, Wilmington, DE (US);

Inventors:

Michael Dauner, Claymont, DE (US);

Lori Ann Maggio-Hall, Wilmington, DE (US);

Jean-Francois Tomb, Wilmington, DE (US);

Assignee:

Butamax Advanced Biofuels LLC, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12N 1/00 (2006.01); C12N 9/00 (2006.01); C12N 15/00 (2006.01); C12P 7/16 (2006.01); C07H 21/04 (2006.01); C12N 15/81 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 9/88 (2006.01); C12N 15/52 (2006.01); C12N 15/74 (2006.01); C12P 7/18 (2006.01); C12P 7/26 (2006.01); C12P 7/46 (2006.01); C12P 7/56 (2006.01); C12P 13/06 (2006.01); C12P 13/08 (2006.01);
U.S. Cl.
CPC ...
C12N 15/81 (2013.01); C12N 9/0008 (2013.01); C12N 9/1029 (2013.01); C12N 9/88 (2013.01); C12N 15/52 (2013.01); C12N 15/74 (2013.01); C12P 7/16 (2013.01); C12P 7/18 (2013.01); C12P 7/26 (2013.01); C12P 7/46 (2013.01); C12P 7/56 (2013.01); C12P 13/06 (2013.01); C12P 13/08 (2013.01); C12Y 102/07001 (2013.01); C12Y 114/15003 (2013.01); C12Y 118/01001 (2013.01); C12Y 118/01002 (2013.01); C12Y 203/01008 (2013.01); C12Y 203/01054 (2013.01); C12Y 401/01001 (2013.01); C12Y 401/02009 (2013.01); Y02E 50/10 (2013.01); Y02P 20/52 (2015.11);
Abstract

The present invention is related to recombinant host cells comprising: (i) at least one deletion, mutation, and/or substitution in an endogenous gene encoding a polypeptide that converts pyruvate to acetaldehyde, acetyl-phosphate, or acetyl-CoA; and (ii) a heterologous polynucleotide encoding a polypeptide having phosphoketolase activity. The present invention is also related to recombinant host cells further comprising (iii) a heterologous polynucleotide encoding a polypeptide having phosphotransacetylase activity.


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