The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2017

Filed:

May. 20, 2013
Applicants:

Korea Institute of Radiological & Medical Sciences, Seoul, KR;

Inha University Research and Business Foundation, Incheon, KR;

Inventors:

Jae-Seon Lee, Seoul, KR;

Seung Hee Jung, Seoul, KR;

Bong Cho Kim, Gyeonggi-do, JP;

Hyung Chul Lee, Seoul, KR;

Na-Kyung Han, Seoul, KR;

Mi-Na Hong, Seoul, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61K 31/713 (2013.01); C12N 2310/14 (2013.01); C12Y 207/07004 (2013.01);
Abstract

Provided is a composition for inducing tumor cell senescence and a method for inducing tumor cell senescence using the same. The composition can inhibit a PAPSS2 gene in a tumor cell to thereby induce senescence of the tumor cell, and if the composition is used concurrently with irradiation of the tumor cell, the composition can improve the sensitivity of the tumor cell to radiation.


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