The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2017
Filed:
Sep. 05, 2014
Applicants:
Cheryl Jorcyk, Boise, ID (US);
Dong Xu, Boise, ID (US);
Inventors:
Cheryl Jorcyk, Boise, ID (US);
Dong Xu, Boise, ID (US);
Assignee:
Boise State University, Boise, ID (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); A61K 31/00 (2006.01); A61K 39/395 (2006.01); A61K 31/4178 (2006.01); A61K 45/06 (2006.01); A61K 31/165 (2006.01); A61K 31/522 (2006.01); A61K 31/404 (2006.01); A61K 31/4025 (2006.01); A61K 31/4184 (2006.01); A61K 31/53 (2006.01); A61K 31/513 (2006.01); A61K 31/427 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/248 (2013.01); A61K 31/165 (2013.01); A61K 31/404 (2013.01); A61K 31/4025 (2013.01); A61K 31/4178 (2013.01); A61K 31/4184 (2013.01); A61K 31/427 (2013.01); A61K 31/513 (2013.01); A61K 31/522 (2013.01); A61K 31/53 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01);
Abstract
A method of treating cancer or metastasis is provided involving administering at least one oncostatin M (OSM) antagonist to a subject, wherein the subject has been diagnosed with cancer. Administration of an OSM antagonist such as a small molecule pharmaceutical is provided as well as an anti-OSM antibody, an anti-OSM aptamer, and an OSM mRNA antagonist. The OSM antagonists were found to inhibit or prevent tumor cell detachment, proliferation and metastasis in several cancer types.