The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9550821 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 24, 2017

Filed:

Dec. 14, 2012
Applicant:

Alizé Pharma Sas, Écully, FR;

Inventors:

Aart Jan Van Der Lely, Bergschenhoek, NL;

Thierry Abribat, Ste-Foy-les-Lyon, FR;

Assignee:

Alize Pharma SAS, Ecully, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 3/04 (2006.01); C07K 14/575 (2006.01); A61K 38/25 (2006.01); A61K 38/08 (2006.01); A61K 38/22 (2006.01); G01N 33/74 (2006.01); C07K 5/10 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01);
U.S. Cl.
CPC ...
C07K 14/575 (2013.01); A61K 38/08 (2013.01); A61K 38/2264 (2013.01); A61K 38/25 (2013.01); C07K 5/10 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); G01N 33/74 (2013.01); G01N 2333/62 (2013.01); G01N 2800/042 (2013.01); G01N 2800/044 (2013.01); G01N 2800/52 (2013.01);
Abstract

A method and a composition for decreasing ghrelin levels and/or decreasing ghrelin/unacylated ghrelin ratio in a subject, the method comprising administering an effective amount of unacylated ghrelin, a fragment thereof, an analog thereof and/or pharmaceutically acceptable salts thereof to the subject wherein a reduction in ghrelin levels and/or a reduction in ghrelin/unacylated ghrelin ratio is beneficial to the subject. Also, use of ghrelin level and/or ghrelin/unacylated ghrelin ratio as biomarkers for determining a subject's likelihood of responding to and/or benefiting from administration of unacylated ghrelin.


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