The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2017

Filed:

Jul. 26, 2013
Applicant:

Biogen MA Inc., Cambridge, MA (US);

Inventors:

Kevin Guckian, Northborough, MA (US);

Gnanasambandam Kumaravel, Lexington, MA (US);

Bin Ma, Arlington, MA (US);

Sha Mi, Belmont, MA (US);

Hairuo Peng, Needham, MA (US);

Zhaohui Shao, Brookline, MA (US);

Lihong Sun, Lexington, MA (US);

Arthur Taveras, Boston, MA (US);

Zhili Xin, Lexington, MA (US);

Lei Zhang, Westford, MA (US);

Assignee:

BIOGEN MA INC., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 229/48 (2006.01); C07D 223/06 (2006.01); C07D 221/22 (2006.01); C07D 209/52 (2006.01); C07D 211/62 (2006.01); C07D 295/096 (2006.01); A61K 31/5375 (2006.01); A61K 31/439 (2006.01); A61K 31/46 (2006.01); A61K 31/445 (2006.01); A61K 31/196 (2006.01); A61K 31/136 (2006.01); C07F 7/08 (2006.01); A61K 45/06 (2006.01); A61K 31/195 (2006.01); A61K 31/41 (2006.01); A61K 31/4709 (2006.01); A61K 31/4725 (2006.01); A61K 31/5513 (2006.01); C07D 215/38 (2006.01); C07D 217/22 (2006.01); C07D 401/04 (2006.01); C07D 471/08 (2006.01); C07C 217/58 (2006.01); C07C 229/46 (2006.01); C07C 233/61 (2006.01); C07C 235/66 (2006.01); A61K 31/397 (2006.01); A61K 31/4545 (2006.01); A61K 31/47 (2006.01); A61K 31/495 (2006.01); A61K 31/496 (2006.01); A61K 31/506 (2006.01); A61K 31/551 (2006.01); A61K 31/695 (2006.01); C07C 211/38 (2006.01); C07D 205/04 (2006.01); C07D 213/74 (2006.01); C07D 215/20 (2006.01); C07D 401/06 (2006.01);
U.S. Cl.
CPC ...
C07F 7/0809 (2013.01); A61K 31/195 (2013.01); A61K 31/196 (2013.01); A61K 31/397 (2013.01); A61K 31/41 (2013.01); A61K 31/439 (2013.01); A61K 31/4545 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 31/4725 (2013.01); A61K 31/495 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/551 (2013.01); A61K 31/5513 (2013.01); A61K 31/695 (2013.01); A61K 45/06 (2013.01); C07C 211/38 (2013.01); C07C 217/58 (2013.01); C07C 229/46 (2013.01); C07C 233/61 (2013.01); C07C 235/66 (2013.01); C07D 205/04 (2013.01); C07D 213/74 (2013.01); C07D 215/20 (2013.01); C07D 215/38 (2013.01); C07D 217/22 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 471/08 (2013.01); C07F 7/0818 (2013.01); C07C 2101/14 (2013.01); C07C 2102/08 (2013.01); C07C 2102/10 (2013.01); C07C 2102/42 (2013.01); C07C 2102/44 (2013.01); C07C 2102/46 (2013.01); C07C 2102/50 (2013.01); C07C 2103/62 (2013.01); C07C 2103/74 (2013.01);
Abstract

Compounds of formula (I) can modulate the activity of one or more SIP receptors and/or the activity of autotaxin (ATX).


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