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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9550783 B1

PDFFull Text
Date of Patent:
Jan. 24, 2017

Filed:

May. 19, 2014

Biaryl heterocyclic compounds and methods of making and using the same

Applicant:

Melinta Therapeutics, Inc., New Haven, CT (US);

Inventors:

Jiacheng Zhou, Newark, DE (US);

Ashoke Bhattacharjee, Cheshire, CT (US);

Shili Chen, Cheshire, CT (US);

Yi Chen, West Roxbury, MA (US);

Jay J. Farmer, Ithaca, NY (US);

Joel A. Goldberg, New Orleans, LA (US);

Roger Hanselmann, Branford, CT (US);

Rongliang Lou, Cheshire, CT (US);

Alia Orbin, Macungie, PA (US);

Adegboyega K. Oyelere, Marietta, GA (US);

Joseph M. Salvino, Chester Springs, PA (US);

Dane M. Springer, Yardley, PA (US);

Jennifer Tran, Guilford, CT (US);

Deping Wang, Furlong, PA (US);

Yusheng Wu, New Haven, CT (US);

Assignee:

MELINTA THERAPEUTICS, INC., New Haven, CT (US);

Attorney:

Wilmer Cutler Pickering Hale and Dorr

Primary Examiner:

Kamal Saeed

Int. Cl.
CPC ...
A01N 43/80 (2006.01); C07D 261/04 (2006.01); C07D 487/04 (2006.01); C07D 263/20 (2006.01); C07D 263/32 (2006.01); C07D 413/10 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/10 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 453/02 (2006.01); C07D 473/00 (2006.01); C07D 263/24 (2006.01); C07D 473/34 (2006.01); C07D 263/26 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 263/20 (2013.01); C07D 263/24 (2013.01); C07D 263/26 (2013.01); C07D 263/32 (2013.01); C07D 413/10 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/10 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 453/02 (2013.01); C07D 471/04 (2013.01); C07D 473/00 (2013.01); C07D 473/34 (2013.01);
Abstract

The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents.

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