The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2017
Filed:
Mar. 07, 2013
Medivation Technologies, Inc., San Francisco, CA (US);
Andrew Asher Protter, Palo Alto, CA (US);
Sarvajit Chakravarty, Mountain View, CA (US);
Rajendra Parasmal Jain, Pune, IN;
Michael John Green, Half Moon Bay, CA (US);
MEDIVATION TECHNOLOGIES, INC., San Francisco, CA (US);
Abstract
Hydrogenated pyrido[4,3-b]indoles, pyrido[3,4-b]indoles and azepino[4,5-b]indoles are described. The compounds may bind to and are antagonists of the adrenergic receptor α. The compounds may also bind to and are an antagonist of the adrenergic receptor α; or the compounds are not antagonists of the adrenergic receptor αand the compounds are administered in conjunction with a second agent that reduces, or is expected to reduce, blood pressure in an individual. The compounds may find use in therapy, e.g., to regulate blood glucose level, increase insulin secretion and treat diseases or conditions that are, or are expected to be, responsive to an increase in insulin production. Use of the compounds to treat type 2 diabetes is particularly described.