The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2017

Filed:

Aug. 05, 2014
Applicant:

University of Notre Dame Du Lac, Notre Dame, IN (US);

Inventors:

Ryan K. Roeder, Granger, IN (US);

Matthew J. Meagher, Notre Dame, IN (US);

Robert J. Kane, South Bend, IN (US);

Assignee:

University of Notre Dame Du Lac, Notre Dame, IN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); A61L 27/40 (2006.01); A61L 27/24 (2006.01); A61L 27/12 (2006.01); A61P 19/08 (2006.01); A61L 27/46 (2006.01);
U.S. Cl.
CPC ...
A61L 27/54 (2013.01); A61K 38/18 (2013.01); A61K 38/1866 (2013.01); A61K 38/1875 (2013.01); A61L 27/46 (2013.01); A61L 27/56 (2013.01); A61L 2300/414 (2013.01); A61L 2430/02 (2013.01);
Abstract

The invention provides a novel composite bone graft system utilizing a porous collagen scaffold having a matrix impregnated with calcium phosphate particles and more than one bioactive agent, one of which is conjugated to the matrix. The graft system exhibits increased mechanical strength and osteogenic properties by providing sites for tissue attachment and propagation. The bioactive agents are delivered to the scaffold via different mechanisms to enable sequential and sustained release of the bioactive agents over time.


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