The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2017
Filed:
Oct. 02, 2013
Applicants:
Rutgers, the State University of New Jersey, New Brunswick, NJ (US);
Georgetown University, N.W., WA (US);
Inventors:
Siang-Yo Lin, East Brunswick, NJ (US);
Joseph R. Bertino, Brantford, CT (US);
Chen-Yong Lin, Falls Church, VA (US);
Michael Johnson, Rockville, MD (US);
Assignees:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, New Brunswick, NJ (US);
GEORGETOWN UNIVERSITY, Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); C07K 16/40 (2006.01); A61K 31/00 (2006.01); A61K 31/704 (2006.01); A61K 31/7048 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48646 (2013.01); A61K 31/704 (2013.01); A61K 31/7048 (2013.01); A61K 47/484 (2013.01); A61K 47/48407 (2013.01); A61K 47/48569 (2013.01); C07K 16/40 (2013.01); C07K 2317/24 (2013.01); C07K 2317/76 (2013.01); C07K 2319/55 (2013.01);
Abstract
Disclosed are antibody drug conjugates (ADC) that include highly potent toxic agents with specific antibodies to target tumors. Also disclosed are related antibodies, polypeptides, nucleic acids, host cells, compositions, and uses.