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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9549983 B1

PDFFull Text
Date of Patent:
Jan. 24, 2017

Filed:

Apr. 17, 2014

Amine cationic lipids and uses thereof

Applicant:

Dicerna Pharmaceuticals, Inc., Watertown, MA (US);

Inventors:

Bob Dale Brown, Millington, NJ (US);

Sujit Kumar Basu, Newton, MA (US);

David A. Schwartz, Encinitas, CA (US);

Allister Fraser, Encinitas, CA (US);

Assignee:

Dicerna Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:

Sunstein Kann Murphy & Timbers LLP

Primary Examiner:

Janet Epps-Smith

Int. Cl.
CPC ...
A61K 47/18 (2006.01); A61K 31/713 (2006.01); A61K 47/22 (2006.01); C12N 15/113 (2010.01); A61K 9/127 (2006.01); C12N 15/11 (2006.01); C12N 15/88 (2006.01); C07D 233/61 (2006.01); C07D 233/64 (2006.01); C07D 239/42 (2006.01); C07D 241/04 (2006.01); C07C 237/06 (2006.01); C07D 295/03 (2006.01); C07D 211/36 (2006.01); C07D 295/13 (2006.01); C07D 295/15 (2006.01); C07C 211/21 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/18 (2013.01); A61K 9/127 (2013.01); A61K 31/713 (2013.01); A61K 47/22 (2013.01); C07C 211/21 (2013.01); C07C 237/06 (2013.01); C07D 211/36 (2013.01); C07D 233/61 (2013.01); C07D 233/64 (2013.01); C07D 239/42 (2013.01); C07D 241/04 (2013.01); C07D 295/03 (2013.01); C07D 295/13 (2013.01); C07D 295/15 (2013.01); C12N 15/111 (2013.01); C12N 15/1137 (2013.01); C12N 15/88 (2013.01); A61K 38/00 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01); C12Y 204/02008 (2013.01);
Abstract

The present invention relates to lipid compounds and uses thereof. In particular, the compounds include a class of cationic lipids having an amine moiety, such as an amino-amine or an amino-amide moiety. The lipid compounds are useful for in vivo or in vitro delivery of one or more agents (e.g., a polyanionic payload or an antisense payload, such as an RNAi agent).

Find Patent Forward Citations

Brown, Bob. (2017). Amine cationic lipids and uses thereof (U.S. Patent No. 9549983). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9549983

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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