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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9549972 B1

PDFFull Text
Date of Patent:
Jan. 24, 2017

Filed:

Aug. 06, 2015

Mhc-i restricted epitopes containing non-natural amino acid residues

Applicant:

Purdue Pharma L.p., Stamford, CT (US);

Inventors:

Donald J. Kyle, Yardley, PA (US);

Daniel A. Soltis, Cleveland Heights, OH (US);

Lynda G. Tussey, Princeton, NJ (US);

Assignee:

Purdue Pharma L.P., Stamford, CT (US);

Attorney:

Sterne, Kessler, Goldstein & Fox, P.L.L.C.

Primary Examiner:

Satyanarayana R Gudibande

Int. Cl.
CPC ...
A61K 38/08 (2006.01); C07K 4/00 (2006.01); C07K 7/06 (2006.01); A61K 39/00 (2006.01); C07K 14/47 (2006.01); C12N 9/02 (2006.01); C12N 9/12 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0005 (2013.01); C07K 7/06 (2013.01); C07K 14/4747 (2013.01); C07K 14/4748 (2013.01); C12N 9/0077 (2013.01); C12N 9/1241 (2013.01); G01N 33/505 (2013.01); G01N 33/6878 (2013.01); A61K 39/00 (2013.01); G01N 2333/70539 (2013.01); G01N 2500/04 (2013.01); G01N 2500/10 (2013.01);
Abstract

The invention provides for the synthesis of more effective generators of a T-cell immune response by providing peptide derivatives that are MHC class I-restricted antigens. The peptide derivatives of the present invention are prepared or derived from a parent peptide of 8 to 11 amino acid residues in length, wherein the peptide derivative contains a non-natural amino acid substituted in place of a naturally-occurring amino acid residue at one or more primary anchor positions in the parent peptide or at position 6, position 7, or the C-terminus.

Find Patent Forward Citations

Kyle, Donald. (2017). Mhc-i restricted epitopes containing non-natural amino acid residues (U.S. Patent No. 9549972). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9549972

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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