The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2017
Filed:
May. 28, 2010
Applicants:
Robert Tarran, Chapel Hill, NC (US);
Monroe Jack Stutts, Chapel Hill, NC (US);
Scott Donaldson, Chapel Hill, NC (US);
Inventors:
Robert Tarran, Chapel Hill, NC (US);
Monroe Jack Stutts, Chapel Hill, NC (US);
Scott Donaldson, Chapel Hill, NC (US);
Assignee:
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); G01N 33/53 (2006.01); A61K 38/17 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); C07K 14/4703 (2013.01);
Abstract
The present invention relates to the ability of PLUNC proteins, such as SPLUNC1 and SPLUNC2, to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of PLUNC proteins to sodium channels.