The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 17, 2017

Filed:

Dec. 27, 2013
Applicant:

Emerald Therapeutics, Inc., Menlo Park, CA (US);

Inventor:

Daniel J. Kleinbaum, Yardley, PA (US);

Assignee:

Emerald Therapeutics, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06N 3/00 (2006.01); G06F 19/22 (2011.01); G06N 3/12 (2006.01); B82Y 10/00 (2011.01);
U.S. Cl.
CPC ...
G06F 19/22 (2013.01); B82Y 10/00 (2013.01); G06N 3/002 (2013.01); G06N 3/123 (2013.01);
Abstract

Improvement is effected for a nucleic acid-based molecular computing system that is comprised of (i) a nucleic acid structure, (ii) at least one polynucleotide displacement molecule that can bind with the nucleic acid structure under hybridizing conditions, and (iii) a clashing polynucleotide molecule that competes with the polynucleotide displacement molecule for binding the nucleic acid structure under the hybridizing conditions. The method for such improvement entails incorporating chemical modification that inhibits the binding of the clashing molecule and the nucleic acid structure or facilitating the binding of the displacement molecule and the nucleic structure.


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