The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2017
Filed:
Jun. 29, 2011
Fuman Jiang, Shenzhen, CN;
Huifei Chen, Shenzhen, CN;
Xianghua Chai, Shenzhen, CN;
Yuying Yuan, Shenzhen, CN;
Xiuqing Zhang, Shenzhen, CN;
Fang Chen, Shenzhen, CN;
Fuman Jiang, Shenzhen, CN;
Huifei Chen, Shenzhen, CN;
Xianghua Chai, Shenzhen, CN;
Yuying Yuan, Shenzhen, CN;
Xiuqing Zhang, Shenzhen, CN;
Fang Chen, Shenzhen, CN;
BGI HEALTH SERVICE CO., LTD., Shenzhen, Guangdong, CN;
Abstract
The current invention is directed to methods for noninvasive detection of fetal genetic abnormalities by large-scale sequencing of nucleotides from maternal biological sample. Further provided are methods to remove GC bias from the sequencing results according to the difference in GC content of a chromosome. The current invention not only makes the detection much more accurate but also represents a comprehensive method for fetal aneuploidy detection including sex chromosome disorders such as XO, XXX, XXY, and XYY, etc.