The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2017
Filed:
Sep. 08, 2014
Geneweave Biosciences, Inc., Los Gatos, CA (US);
Diego Ariel Rey, Palo Alto, CA (US);
Shaunak Roy, Sunnyvale, CA (US);
Werner Frei, Los Gatos, CA (US);
Bruce J. Richardson, Los Gatos, CA (US);
Ryan C. Griswold, Los Gatos, CA (US);
Damian S. Matthews, Capitola, CA (US);
Kenneth G. Olson, San Jose, CA (US);
Victor H. Yee, Castro Valley, CA (US);
GeneWeave Biosciences, Inc., Los Gatos, CA (US);
Abstract
Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity.