The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2017
Filed:
Oct. 24, 2014
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Jogeshwar Mukherjee, Irvine, CA (US);
Aparna Baranwal, Cerritos, CA (US);
Nehal Mahendra Shah, Irvine, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 15/26 (2006.01); C07B 59/00 (2006.01); A61K 51/04 (2006.01); C07C 227/18 (2006.01); C07D 207/09 (2006.01); C07C 245/08 (2006.01); C07D 471/08 (2006.01); C07C 215/16 (2006.01); C07D 277/66 (2006.01); C07C 213/02 (2006.01);
U.S. Cl.
CPC ...
C07H 15/26 (2013.01); A61K 51/04 (2013.01); A61K 51/0446 (2013.01); A61K 51/0448 (2013.01); A61K 51/0453 (2013.01); A61K 51/0468 (2013.01); A61K 51/0491 (2013.01); C07B 59/005 (2013.01); C07C 215/16 (2013.01); C07C 227/18 (2013.01); C07C 245/08 (2013.01); C07D 207/09 (2013.01); C07D 277/66 (2013.01); C07D 471/08 (2013.01); C07C 213/02 (2013.01);
Abstract
Various compositions and methods for Quasi-Amadori products and derivatives thereof are contemplated in which a halogenated carbohydrate is reacted with a primary amino group of an affinity ligand. In especially preferred aspects, the Quasi-Amadori product is formed from 2-fluorodeoxyglucose and an affinity moiety that preferentially or selectively binds to a neural cell or neural structure. Where contemplated compounds includeF, PET imaging using compounds presented herein is especially preferred.