The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2017
Filed:
Sep. 17, 2013
Michael Patrick Dillon, Boston, MA (US);
Mika Lindvall, Oakland, CA (US);
Daniel Poon, Piedmont, CA (US);
Savithri Ramurthy, Arlington, MA (US);
Vivek Rauniyar, Cambridge, MA (US);
Cynthia Shafer, El Sobrante, CA (US);
Sharadha Subramanian, San Ramon, CA (US);
Huw Rowland Tanner, San Francisco, CA (US);
Michael Patrick Dillon, Boston, MA (US);
Mika Lindvall, Oakland, CA (US);
Daniel Poon, Piedmont, CA (US);
Savithri Ramurthy, Arlington, MA (US);
Vivek Rauniyar, Cambridge, MA (US);
Cynthia Shafer, El Sobrante, CA (US);
Sharadha Subramanian, San Ramon, CA (US);
Huw Rowland Tanner, San Francisco, CA (US);
Novartis AG, Basel, CH;
Abstract
The present invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof; as further described herein. The present invention further provides pharmaceutical compositions comprising these compounds, and combinations comprising these compounds combined with or used with a therapeutic co-agent, as well as therapeutic uses of these compounds and compositions. These are useful in the treatment of diseases such as cancer that are associated with activation of ERK1 and/or ERK2, and especially for MAPK pathway dependent cancers showing resistance to Raf and/or MEK inhibitory cancer therapeutics.