The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 17, 2017

Filed:

Oct. 14, 2013
Applicant:

Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;

Inventors:

Pascal Collin, Buc, FR;

Maxim Egorov, Bouguenais, FR;

Bernard Delpech, Clamart, FR;

Joanna Bakala, Paris, FR;

Maria Achab, Gif s/Yvette, FR;

Jérome Bignon, Le Val Saint Germain, FR;

Odile Thoison, Palaiseau, FR;

Michel Benechie, Gif s/Yvette, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/06 (2006.01); C07D 207/333 (2006.01);
U.S. Cl.
CPC ...
C07D 403/06 (2013.01); C07D 207/333 (2013.01);
Abstract

The present invention relates to a compound of formula (I) in which: -m is an integer from 0 to 3, preferably from 0 to 2; n is an integer from 0 to 3, preferably from 0 to 2; m+n≧1; EAG is an electro-attractive group chosen independently from among a halogen atom, an NO, CF, CCI, CN, COH, (C═O)NR, CH═NR, (C═S)OR, (C═O)SR, CSR, SOR, SONR, SOR, P(O)(OR), P(O)(R), B(OR)group where R is a (C-C) alkyl radical, a phenyl group or a hydrogen atom; A is a saturated or unsaturated, linear or branched hydrocarbon chain including 1 to 10 atoms of carbon; and Rand Reach represent independently from one another a hydrogen atom, a CO-(Ci-C6)-alkyl, (C-C) alkyl, phenyl or phenyl-(C-C)-alkyl group, in which Rand Rform, together with the nitrogen atom they carry, a 5- to 15-member heterocycle, optionally substituted by a (C-C) alkyl group; including its stereoisomers and the mixtures thereof, or a pharmaceutically acceptable salt of same.


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