The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2017
Filed:
Aug. 29, 2012
Applicants:
Frédéric Colland, Puiseux en France, FR;
Marie-edith Gourdel, Savigny le Temple, FR;
Inventors:
Frédéric Colland, Puiseux en France, FR;
Marie-Edith Gourdel, Savigny le Temple, FR;
Assignee:
HYBRIGENICS SA, Paris, FR;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); C07D 239/88 (2006.01); C07D 401/06 (2006.01); C07D 409/14 (2006.01); C07D 239/91 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/06 (2013.01); A61K 31/517 (2013.01); A61K 45/06 (2013.01); C07D 239/88 (2013.01); C07D 239/91 (2013.01); C07D 409/14 (2013.01);
Abstract
The present invention relates to quinazolin-4-one compounds of formula (I'), their process of preparation and uses thereof. These compounds are useful as selective and reversible inhibitors of ubiquitin specific proteases, particularly USP7, for treating e.g. cancer, neurodegenerative diseases, inflammatory disorders and viral infections.