The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2017
Filed:
Aug. 06, 2014
Applicant:
Viatar Llc, Lowell, MA (US);
Inventors:
Cornelis Johannes Maria van Rijn, Hengelo, NL;
Ilan K. Reich, Short Hills, NJ (US);
Assignee:
VIATAR LLC, Lowell, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61M 1/34 (2006.01); B01D 61/00 (2006.01);
U.S. Cl.
CPC ...
A61M 1/3482 (2014.02); A61M 1/3431 (2014.02); A61M 1/3472 (2013.01); A61M 1/3486 (2014.02); A61M 1/342 (2013.01); A61M 2202/005 (2013.01); A61M 2202/0014 (2013.01); A61M 2202/0057 (2013.01); A61M 2205/75 (2013.01);
Abstract
A device can be used to retain circulating tumor cells (CTCs). The device can include a cross-flow module with a retentate channel and a permeate channel. A filter in the cross-flow module can separate the retentate channel from the permeate channel. The filter can be constructed such that CTCs are retained in the retentate channel while other cells can pass through the filter into the permeate channel. A recirculation channel can direct a flow from an outlet of the retentate channel back to an inlet of the retentate channel to thereby concentrate CTCs in the retentate flow.