The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 17, 2017

Filed:

May. 13, 2013
Applicant:

Advanced Proteome Therapeutics Inc., Boston, MA (US);

Inventor:

Alexander Krantz, Boston, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 47/48 (2006.01); A61K 38/17 (2006.01); A61K 38/38 (2006.01); A61K 38/40 (2006.01); A61K 45/06 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48246 (2013.01); A61K 38/17 (2013.01); A61K 38/38 (2013.01); A61K 38/40 (2013.01); A61K 45/06 (2013.01); C07K 14/435 (2013.01);
Abstract

The present invention relates to the formation of protein conjugates from proteins chemically modified for linkage to (1) anticancer drug pharmacophores, (2) ligands to biomarkers on cancer cell surfaces, (3) and/or another protein molecule. It provides and specifies new compositions, methods and combinations for tumor, and tumor vasculature targeting and cancer treatment.


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