The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 17, 2017

Filed:

Feb. 27, 2009
Applicants:

Peter Delputte, Kortrijk, BE;

Hans Nauwynck, Zomergem, BE;

Iris Delrue, De Pinte, BE;

Merijn Vanhee, Assebroek, BE;

Inventors:

Peter Delputte, Kortrijk, BE;

Hans Nauwynck, Zomergem, BE;

Iris Delrue, De Pinte, BE;

Merijn Vanhee, Assebroek, BE;

Assignee:

Universiteit Gent, Ghent, BE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); G01N 33/56983 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/552 (2013.01); A61K 2039/55566 (2013.01); C12N 2770/10032 (2013.01); C12N 2770/10034 (2013.01);
Abstract

The invention relates generally to the field of virology. More particularly, the present invention relates to methods for determining the effect of a viral inactivation procedure on the antigenicity of the inactivated virus, in particular, for a virus that is a member of the family Arteriviridae or Coronaviridae or Asfarviridae, in particular, for Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). The invention further provides methods to determine the antigenicity of an inactivated virus as well as methods to screen for anti-viral compounds using any one of the aforementioned methods. Methods of using the inactivated and immunogenic virus thus obtained, in particular, in the manufacture of a vaccine, are also provided by the present invention.


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