The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 17, 2017

Filed:

Dec. 23, 2013
Applicant:

Wisconsin Alumni Research Foundation, Madison, WI (US);

Inventors:

Jess Dreher Reed, Middleton, WI (US);

Christian Gerald Krueger, Cambridge, WI (US);

Sergio Madrigal-Carballo, Madison, WI (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/36 (2006.01); A61K 31/722 (2006.01); A01N 43/16 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 9/19 (2006.01); A61K 9/51 (2006.01); A61K 9/70 (2006.01); A61K 31/715 (2006.01); A61K 39/39 (2006.01); A61K 45/06 (2006.01); A61K 49/22 (2006.01); A61L 29/08 (2006.01); A61L 31/10 (2006.01); A61K 31/353 (2006.01); A61K 9/20 (2006.01); A61K 39/00 (2006.01); A61F 13/00 (2006.01); C08H 7/00 (2011.01);
U.S. Cl.
CPC ...
A61K 31/722 (2013.01); A01N 43/16 (2013.01); A61K 9/0014 (2013.01); A61K 9/06 (2013.01); A61K 9/19 (2013.01); A61K 9/5161 (2013.01); A61K 9/7007 (2013.01); A61K 31/353 (2013.01); A61K 31/715 (2013.01); A61K 39/39 (2013.01); A61K 45/06 (2013.01); A61K 47/36 (2013.01); A61K 49/227 (2013.01); A61L 29/085 (2013.01); A61L 31/10 (2013.01); A23V 2250/21166 (2013.01); A61F 2013/00523 (2013.01); A61F 2013/00676 (2013.01); A61K 9/008 (2013.01); A61K 9/0019 (2013.01); A61K 9/2054 (2013.01); A61K 2039/542 (2013.01); C08H 6/00 (2013.01);
Abstract

The invention provides a composition comprising a matrix of chitosan and a tannin wherein the chitosan is electrostatically bonded to the tannin to form a chitosan-tannin composite material. The chitosan can be partially or fully deacetylated, and the tannin can be a monomeric or an oligomeric proanthocyanidin or a hydrolysable tannin. The chitosan-tannin composite material can be a nanoparticle, a hydrogel film, a bio-foam, or a biogel, or the chitosan-tannin composite material can coat a liposome. The composite materials can be used for drug delivery, for antibacterial and/or antifungal applications, for tissue engineering applications, for wound healing applications, or they can be used as adjuvants for vaccination, including oral vaccinations. The invention also provides methods of preparing the composite materials and their various forms.


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