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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9545417 B1

PDFFull Text
Date of Patent:
Jan. 17, 2017

Filed:

May. 01, 2015

Methods of inhibiting cancer stem cells with hmga1 inhibitors

Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Linda M. Smith Resar, Stevenson, MD (US);

David Huso, Parkton, MD (US);

Leslie Cope, Baltimore, MD (US);

Assignee:

THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);

Attorneys:

Ward and Smith, P.A.

Jerry W. Childers

Primary Examiner:

Amy Bowman

Int. Cl.
CPC ...
C12N 15/85 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 31/7068 (2006.01); G01N 33/574 (2006.01); A61K 31/713 (2006.01); C12Q 1/68 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/7068 (2013.01); A61K 31/713 (2013.01); C12N 15/113 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5748 (2013.01); G01N 33/57484 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01); C12N 2320/30 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01);
Abstract

The presently disclosed subject matter relates to methods of inhibiting cancer stem cells and growth of aggressive and/or poorly differentiated metastatic tumors comprising the cancer stem cells with HMGA1 inhibitors. The presently disclosed subject matter also provides methods of selecting and treating a subject with aggressive and/or poorly differentiated metastatic cancer using HMGA1 inhibitors.

Find Patent Forward Citations

Smith Resar, Linda. (2017). Methods of inhibiting cancer stem cells with hmga1 inhibitors (U.S. Patent No. 9545417). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9545417

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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