The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 17, 2017

Filed:

Aug. 07, 2015
Applicant:

Pharmacyclics Llc, Sunnyvale, CA (US);

Inventors:

Cassandra Shu, Belmont, CA (US);

Harisha Atluri, Palo Alto, CA (US);

Robert Kuehl, San Francisco, CA (US);

Pearl Shwe-Cho Tay, Union City, CA (US);

Ryan Mitchell Minikis, Bend, OR (US);

James Francis Hulvat, Bend, OR (US);

Alexander Jacob McVey, Bend, OR (US);

Ching Wah Chong, Fremont, CA (US);

Assignee:

Pharmacyclics LLC, Sunnyvale, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 9/10 (2006.01); A61K 47/26 (2006.01); A61K 47/38 (2006.01); A61K 47/12 (2006.01); A61K 47/02 (2006.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 9/10 (2013.01); A61K 9/1652 (2013.01); A61K 9/2054 (2013.01); A61K 9/2077 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/26 (2013.01); A61K 47/38 (2013.01);
Abstract

Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including novel pharmaceutical formulations thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.


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