The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2017
Filed:
Dec. 21, 2011
Reijo Laaksonen, Lempäälä, FI;
Kim Ekroos, Espoo, FI;
Reini Hurme, Espoo, FI;
Minna Jänis, Espoo, FI;
Riikka Katainen, Helsinki, FI;
Kirill Tarasov, Espoo, FI;
Reijo Laaksonen, Lempäälä, FI;
Kim Ekroos, Espoo, FI;
Reini Hurme, Espoo, FI;
Minna Jänis, Espoo, FI;
Riikka Katainen, Helsinki, FI;
Kirill Tarasov, Espoo, FI;
ZORA BIOSCIENCES OY, Espoo, FI;
Abstract
The present invention inter alia provides a method, and uses thereof, of predicting statin-induced muscle toxicity or its complications, such as myalgia, myopathy and rhabdomyolysis, by detecting the lipid concentrations or lipid-lipid concentration ratios of a biological sample and comparing them to a control. This method has identified lipid markers that are more specific and sensitive in detecting these statin-induced muscle toxicity than the currently utilized clinical markers. Also provided is an antibody towards said lipids, and the use thereof for predicting, diagnosing, statin-induced muscle toxicity. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of statin-induced muscle toxicity.