The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

Mar. 28, 2014
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

John F. O'Connor, New Rochelle, NY (US);

Galina I. Kovalevskaya, Bronx, NY (US);

Steven Birken, Dumont, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/76 (2006.01); C07K 14/59 (2006.01); C07K 16/26 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/76 (2013.01); C07K 14/59 (2013.01); C07K 16/26 (2013.01); G01N 33/57434 (2013.01); G01N 33/57449 (2013.01); G01N 2333/59 (2013.01); Y10S 435/971 (2013.01); Y10S 436/811 (2013.01); Y10S 436/814 (2013.01); Y10S 436/818 (2013.01);
Abstract

The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.


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