The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

Apr. 19, 2012
Applicants:

Michal Schweiger, Berlin, DE;

Hans Lehrach, Berlin, DE;

Stefan Boerno, Berlin, DE;

Thorsten Schlomm, Hamburg, DE;

Holger Sueltmann, Limburgerhof, DE;

Guido Sauter, Hamburg, DE;

Inventors:

Michal Schweiger, Berlin, DE;

Hans Lehrach, Berlin, DE;

Stefan Boerno, Berlin, DE;

Thorsten Schlomm, Hamburg, DE;

Holger Sueltmann, Limburgerhof, DE;

Guido Sauter, Hamburg, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12Q 2600/154 (2013.01);
Abstract

The invention relates to the identification and selection of novel genomic regions (biomarker) and the identification and selection of novel genomic region combinations which are hypermethylated in subjects with prostate cancer compared to subjects without prostate cancer. Nucleic acids which selectively hybridize to the genomic regions and products thereof are also encompassed within the scope of the invention as are compositions and kits containing said nucleic acids and nucleic acids for use in diagnosing prostate cancer. Further encompassed by the invention is the use of nucleic acids which selectively hybridize to one of the genomic regions or products thereof to monitor disease regression in a patient and the efficacy of therapeutic regimens.


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