The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2017
Filed:
Jan. 25, 2013
Applicant:
Universität Leipzig, Leipzig, DE;
Inventor:
Rolf Gebhardt, Leipzig, DE;
Assignee:
Universität Leipzig, Leipzig, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/22 (2006.01); A61K 31/4436 (2006.01); A61K 31/381 (2006.01); A61K 38/17 (2006.01); A61P 1/16 (2006.01); C12N 15/113 (2010.01); A61K 45/06 (2006.01); C07K 14/575 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1136 (2013.01); A23L 33/13 (2016.08); A61K 31/381 (2013.01); A61K 31/4436 (2013.01); A61K 38/1709 (2013.01); A61K 38/22 (2013.01); A61K 38/2264 (2013.01); A61K 45/06 (2013.01); C12N 15/1135 (2013.01); C12N 15/1138 (2013.01); A23V 2002/00 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2320/30 (2013.01);
Abstract
The present invention relates to the therapeutic use of activators of the zinc finger protein GLI3 in diseases that are associated with reduced Hedgehog signaling in hepatocytes, in particular Polycystic ovary syndrome, Steatosis hepatis, Steatohepatitis and/or Adipositas. The invention further relates to methods of treating an individual with said activator, a pharmaceutical composition comprising said activator and the use of said activator as food supplement.