The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2017
Filed:
Apr. 19, 2016
Mirna Therapeutics, Inc., Austin, TX (US);
Jikui Shen, Dundlak, MD (US);
Kevin Kelnar, Kyle, TX (US);
Jeffrey Shelton, Buda, TX (US);
David Brown, Austin, TX (US);
Peter Campochiaro, Baltimore, MD (US);
The John Hopkins University, Baltimore, MD (US);
ASURAGEN, Inc., Austin, TX (US);
Abstract
The present invention concerns methods and compositions for diagnosing and/or treating vascular diseases including cancer, cardiac diseases, vascular diseases of the eye, and inflammatory diseases. The methods involve measuring the levels of one or multiple miRNAs in patient samples and using the test results to diagnose and/or predict an optimal treatment regimen for the patient. Compositions described in the invention include nucleic acids that function as miRNAs or miRNA inhibitors that can be introduced to a patient to reduce or increase vascularization as needed.