The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

Mar. 06, 2014
Applicant:

Genmab A/s, Copenhagen, DK;

Inventors:

Jan Van De Winkel, Zeist, NL;

Paul Parren, Odijk, NL;

Willem Karel Bleeker, Amsterdam, NL;

Klaus Edvardsen, Klampenborg, DK;

Jeroen Lammerts Van Bueren, Harderwijk, NL;

Thomas Valerius, Neuwittenbek, DE;

Michael Dechant, Bordesholm, DE;

Wencke Weisner, Bremen, DE;

Sven Berger, Haute-Savoie, FR;

Assignee:

GENMAB A/S, Copenhagen, DK;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/40 (2006.01); C07K 16/44 (2006.01); C07K 16/46 (2006.01); G01N 33/573 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); C07K 16/2863 (2013.01); C07K 16/44 (2013.01); C07K 16/468 (2013.01); G01N 33/573 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/54 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The invention relates to novel methods for the treatment of tumors, comprising administration of a bispecific antibody or a combination of two or more non-cross-blocking antibodies that recognize the same target antigen or antigenic complex. In particular, the invention relates to a method for inducing complement-mediated cell killing in the treatment of a tumor, said method comprising combined administration, to a human being in need thereof, of a first antibody and a second antibody, wherein


Find Patent Forward Citations

Loading…