The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2017
Filed:
Jan. 07, 2015
Biotest Ag, Dreieich, DE;
Frank Osterroth, Dietzenbach, DE;
Christoph Uherek, Seligenstadt, DE;
Christoph Bruecher, Eschborn, DE;
Peter Röttgen, Ladenburg, DE;
Benjamin Daelken, Frankfurt am Main, DE;
André Engling, Bad Homburg, DE;
Chantal Zuber, Frankfurt am Main, DE;
Niklas Czeloth, Dreieich, DE;
BIOTEST AG, Dreieich, DE;
Abstract
Provided is a humanized or chimeric antibody or fragment thereof capable of binding to interleukin-10 (IL-10), wherein said antibody or fragment thereof: (i) binds to the same region of IL-10 as the IL-10 receptor α (IL-I10Ra) and is not capable of binding IL-10 when the IL-10 is bound to the IL-10 receptor; and (ii) binds to IL-10 in homodimeric form by binding a discontinuous epitope comprising residues of both monomers. Further provided are related products and methods involving the use of the antibody or fragment thereof.