The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

Oct. 05, 2012
Applicants:

Ac Immune S.a., Lausanne, CH;

Katholieke Universiteit Leuven, Leuven, BE;

Inventors:

Andrea Pfeifer, St-Legier, CH;

Andreas Muhs, Pully, CH;

Maria Pihlgren, Mont-sur-Lausanne, CH;

Oskar Adolfsson, Bercher, CH;

Fred Van Leuven, Linden, BE;

Assignees:

AC IMMUNE S.A., Lausanne, CH;

KATHOLIEKE UNIVERSITEIT LEUVEN, Leuven, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 21/08 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01); C07K 16/18 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 39/0005 (2013.01); A61K 39/3955 (2013.01); G01N 33/6896 (2013.01); A61K 2039/505 (2013.01); C07K 2317/30 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); G01N 2800/2821 (2013.01);
Abstract

The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles, in particular, the invention relates to antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers and to methods and compositions involving said antibodies for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease (AD).


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