The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

Feb. 01, 2012
Applicants:

Sandra Verploegen, Nieuwegein, NL;

Marije Overdijk, Utrecht, NL;

Riemke Van Dijkhuizen, Zeist, NL;

Willem Karel Bleeker, Amsterdam, NL;

Patrick Van Berkel, Utrecht, NL;

Paul Parren, Odijk, NL;

Steen Lisby, Frederiksberg, DK;

Inventors:

Sandra Verploegen, Nieuwegein, NL;

Marije Overdijk, Utrecht, NL;

Riemke Van Dijkhuizen, Zeist, NL;

Willem Karel Bleeker, Amsterdam, NL;

Patrick Van Berkel, Utrecht, NL;

Paul Parren, Odijk, NL;

Steen Lisby, Frederiksberg, DK;

Assignee:

GENMAB A/S, Copenhagen, DK;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C07K 16/42 (2006.01); C07K 16/18 (2006.01); A61K 47/48 (2006.01); A61K 51/10 (2006.01); A61K 31/7088 (2006.01); A61K 35/17 (2015.01); A61K 35/76 (2015.01); A61K 38/16 (2006.01); A61K 38/19 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 31/7088 (2013.01); A61K 35/17 (2013.01); A61K 35/76 (2013.01); A61K 38/162 (2013.01); A61K 38/19 (2013.01); A61K 39/39533 (2013.01); A61K 45/06 (2013.01); A61K 47/48561 (2013.01); A61K 51/1027 (2013.01); C07K 16/2833 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/73 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01);
Abstract

Isolated human monoclonal antibodies which bind to human CD74 and related antibody-drug conjugates are disclosed. Pharmaceutical compositions comprising the antibodies or antibody-drug conjugates, and therapeutic and diagnostic methods for using the antibodies and/or antibody-drug conjugates, are also disclosed.


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