The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

May. 14, 2013
Applicants:

Abbvie Inc., North Chicago, IL (US);

Abbvie Deutschland Gmbh & Co. KG, Wiesbaden, DE;

Inventors:

Stefan Barghorn, Mannheim, DE;

Heinz Hillen, Hassloch, DE;

Boris Labkovsky, Wales, MA (US);

Andreas R. Striebinger, Speyer, DE;

Patrick Keller, Darmstadt, DE;

Ulrich Ebert, Mannheim, DE;

Assignees:

ABBVIE DEUTSCHLAND GMBH & CO. KG, Wiesbaden, DE;

ABBVIE INC., North Chicago, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/18 (2006.01); C07K 14/47 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); C07K 14/4711 (2013.01); A61K 38/00 (2013.01);
Abstract

Anti-Aβ globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies. The present invention relates to anti-Aβ globulomer antibodies having a binding affinity to Aβ(20-42) globulomer that is greater than the binding affinity of the antibody to Aβ(1-42) globulomer, antigen-binding moieties thereof, hybridomas producing said antibodies, nucleic acids encoding said antibodies, vectors comprising said nucleic acids, host cells comprising said vectors, methods of producing said antibodies, compositions comprising said antibodies, therapeutic and diagnostic uses of said antibodies and corresponding methods relating to Alzheimer's disease and other amyloidoses.


Find Patent Forward Citations

Loading…