The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2017
Filed:
Jan. 16, 2014
Sanofi, Paris, FR;
Katrin Lorenz, Frankfurt am Main, DE;
Kristin Breitschopf, Frankfurt am Main, DE;
Hartmut Strobel, Frankfurt am Main, DE;
Maria Mendez-Perez, Frankfurt am Main, DE;
Li-hsing Wang, Frankfurt am Main, DE;
Alexander Schiffer, Frankfurt am Main, DE;
Joseph T. Kim, Bridgewater, NJ (US);
Hans-Peter Nestler, Bridgewater, NJ (US);
Mark Drew, Bridgewater, NJ (US);
SANOFI, Paris, FR;
Abstract
The present invention relates to compounds of the formula (I), wherein R1, R11, R12 and X have the meanings indicated in the claims. The compounds of formula I are valuable pharmacologically active compounds. They are highly potent and selective soluble epoxide hydrolase inhibitors and are suitable, for example, for the therapy and prophylaxis of renal failure, diabetic nephropathy, type 2 diabetes mellitus, inflammation or could show beneficial effects in pain, dyslipidemia and atherosclerosis. The invention furthermore relates to processes for the preparation of compounds of the formula (I), their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.