The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

Oct. 18, 2013
Applicants:

Commissariat a L'energie Atomique ET Aux Energies Alternatives, Paris, FR;

Institut Curie, Paris, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Inventors:

Daniel Gillet, Paris, FR;

Julien Barbier, Gif-sur-Yvette, FR;

Ludger Johannes, Courbevoie, FR;

Jean-Christophe Cintrat, Igny, FR;

Romain Noel, Trevou-Treguinec, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 409/04 (2006.01); C07D 409/14 (2006.01); C07D 239/91 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 409/04 (2013.01); C07D 239/91 (2013.01); C07D 409/14 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention concerns a new family of 2,3-dihydroquinazolin-4(1H)-one compounds of general formula (I), and the use thereof as inhibitors of the toxic effects of toxins with intracellular activity, such as ricin or Shiga toxin, for example, using retrograde transport to intoxicate cells.


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