The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

Dec. 21, 2012
Applicant:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Inventors:

Harvey Rubin, Philadelphia, PA (US);

Takahiro Yano, Narberth, PA (US);

Sacha Kassovska-Bratinova, Havertown, PA (US);

Norman Schechter, Philadelphia, PA (US);

Jiah Shin Teh, Baltimore, MD (US);

Jeffrey Winkler, Wynnewood, PA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 241/46 (2006.01); A61K 31/50 (2006.01); A61K 31/498 (2006.01);
U.S. Cl.
CPC ...
C07D 241/46 (2013.01); A61K 31/498 (2013.01);
Abstract

The present invention includes a method of treating or preventing a disease or disorder such as a mycobacterial infection, a Gram-positive bacterium infection, a yeast infection, an inflammatory condition, an auto-immune disorder and/or a proliferative disorder in a subject in need thereof. The method comprises administering to the subject a therapeutically effective amount of at least one compound of the invention, which includes clofazimine derivatives.


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