The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

Oct. 15, 2013
Applicant:

Ormco Corporation, Orange, CA (US);

Inventor:

Alfred David Johnson, Berkeley, CA (US);

Assignee:

Ormco Corporation, Orange, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C30B 33/00 (2006.01); C30B 31/00 (2006.01); C30B 15/36 (2006.01); C30B 29/52 (2006.01); A61L 31/14 (2006.01); A61L 27/04 (2006.01); A61L 27/50 (2006.01); A61L 31/02 (2006.01); C22C 9/01 (2006.01); C30B 15/00 (2006.01);
U.S. Cl.
CPC ...
A61L 31/14 (2013.01); A61L 27/047 (2013.01); A61L 27/50 (2013.01); A61L 31/022 (2013.01); C22C 9/01 (2013.01); C30B 15/00 (2013.01); C30B 29/52 (2013.01); C30B 31/00 (2013.01); C30B 33/005 (2013.01); A61L 2400/16 (2013.01); C30B 15/36 (2013.01);
Abstract

We describe herein biocompatible single crystal Cu-based shape memory alloys (SMAs). In particular, we show biocompatibility based on MEM elution cell cytotoxicity, ISO intramuscular implant, and hemo-compatibility tests producing negative cytotoxic results. This biocompatibility may be attributed to the formation of a durable oxide surface layer analogous to the titanium oxide layer that inhibits body fluid reaction to titanium nickel alloys, and/or the non-existence of crystal domain boundaries may inhibit corrosive chemical attack. Methods for controlling the formation of the protective aluminum oxide layer are also described, as are devices including such biocompatible single crystal copper-based SMAs.


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