The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

May. 17, 2013
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Robert Wood, Lutherville, MD (US);

Hai-Quan Mao, Baltimore, MD (US);

Corinne Keet, Baltimore, MD (US);

Russell Martin, Los Gatos, CA (US);

Assignee:

John Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/35 (2006.01); A61K 47/38 (2006.01); A61K 45/06 (2006.01); A61K 47/10 (2006.01); A61K 9/00 (2006.01); A61K 9/70 (2006.01); A61K 47/26 (2006.01); B29C 39/02 (2006.01); A61K 47/32 (2006.01); B29L 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/38 (2013.01); A61K 9/006 (2013.01); A61K 9/7007 (2013.01); A61K 9/7015 (2013.01); A61K 39/35 (2013.01); A61K 45/06 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01); B29C 39/02 (2013.01); A61K 47/32 (2013.01); B29L 2007/00 (2013.01);
Abstract

The present invention provides a thin mucoadhesive sublingual film composition which provides improved allergen delivery and efficacy at a smaller dose while prolonging the contact time between the allergen and oral antigen presenting cells (APCs), and therefore minimizing the risk of systemic side effects. The thin film compositions of the present invention are also easier to standardize, and removes any need for measuring allergen doses at the physician's office, and which allows for a simplified dosing schedule. Methods of making the thin film compositions and methods for their use are also disclosed.


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