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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9539330 B1

PDFFull Text
Date of Patent:
Jan. 10, 2017

Filed:

Nov. 09, 2015

Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy

Applicant:

Jazz Pharmaceuticals, Inc., Palo Alto, CA (US);

Inventors:

Harry Cook, Eden Prairie, MN (US);

Martha Hamilton, St. Paul, MN (US);

Douglas Danielson, Wyoming, MI (US);

Colette Goderstad, St. Paul, MN (US);

Dayton T. Reardan, Shorewood, MN (US);

Assignee:

Jazz Pharmaceuticals, Inc., Palo Alto, CA (US);

Attorney:

Schwegman Lundberg & Woessner, P.A.

Primary Examiner:

Jeffrey S Lundgren

Assistant Examiner:

Stephanie Springer

Int. Cl.
CPC ...
A01N 37/00 (2006.01); A01N 31/00 (2006.01); A61K 31/19 (2006.01); A61K 31/045 (2006.01); A61K 47/14 (2006.01); A61K 9/00 (2006.01); A61K 31/191 (2006.01); A61K 47/02 (2006.01); A61K 47/08 (2006.01); A61K 47/12 (2006.01); A61J 1/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/14 (2013.01); A61J 1/00 (2013.01); A61K 9/0019 (2013.01); A61K 9/0095 (2013.01); A61K 31/19 (2013.01); A61K 31/191 (2013.01); A61K 47/02 (2013.01); A61K 47/08 (2013.01); A61K 47/12 (2013.01);
Abstract

Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gammahydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorders, including narcolepsy, with these stable formulations of GHB. The present invention also provides methods to treat alcohol and opiate withdrawal, reduced levels of growth hormone, increased intracranial pressure, and physical pain in a patient.

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