The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

Nov. 26, 2008
Applicants:

Matthew R. Pincus, Brooklyn, NY (US);

Josef Michl, Little Neck, NY (US);

Ehsan Sarafraz-yazdi, New York, NY (US);

Inventors:

Matthew R. Pincus, Brooklyn, NY (US);

Josef Michl, Little Neck, NY (US);

Ehsan Sarafraz-Yazdi, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/155 (2006.01); A61K 45/06 (2006.01); A61K 31/4995 (2006.01); A61K 38/10 (2006.01); A61K 38/17 (2006.01); A61K 47/48 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 31/155 (2013.01); A61K 31/4995 (2013.01); A61K 38/10 (2013.01); A61K 38/1709 (2013.01); A61K 38/1758 (2013.01); A61K 47/48023 (2013.01); C07K 14/4746 (2013.01); C07K 2319/03 (2013.01);
Abstract

A method of treating cancer in a subject, including: providing a subject having a plurality of cancer cells; and administering to the subject, a therapeutically effective amount of a composition including: an HDM-2 binding component; and a membrane resident component, the membrane resident component bound to the HDM-2 binding component. Also provided are a method of selectively necrosing cancer cells, a method of causing membranolysis in cancer cells, and a cancer treatment composition.


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