The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

May. 28, 2012
Applicants:

Michael Good, Queensland, AU;

Terry W. Spithill, Bundoora, AU;

Moses Lee, Holland, MI (US);

Inventors:

Michael Good, Queensland, AU;

Terry W. Spithill, Bundoora, AU;

Moses Lee, Holland, MI (US);

Assignees:

Griffth University, Nathan, Queensland, AU;

La Trobe University, Bundoora, Victoria, AU;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/015 (2006.01); C07K 14/445 (2006.01);
U.S. Cl.
CPC ...
A61K 39/015 (2013.01); C07K 14/445 (2013.01); A61K 2039/522 (2013.01);
Abstract

An immunogenic composition for use as a blood-stage malaria vaccine, a method of producing the immunogenic composition and a method of treatment of malaria are provided. The immunogenic composition includes isolated or purified merozoites, or red blood cells infected with merozoites, treated with centanamycin or tafuramycin A. The immunogenic composition does not include an adjuvant. A single dose of the immunogenic composition is sufficient to protect an animal against subsequent malaria infection by the same isolate, strain or species ofused in the immunogenic composition, or by one or more heterologous isolates, strains or species of


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