The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

Jun. 26, 2013
Applicant:

Universidad Nacional Autónoma DE México, Mexico City, MX;

Inventors:

Jaime Mas Oliva, Distrito Federal, MX;

Blanca Alicia Delgado Coello, Distrito Federal, MX;

Victor Guadalupe García Gonzalez, Estado de Mexico, MX;

Armando Perez Torres, Distrito Federal, MX;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/74 (2015.01); A61K 47/48 (2006.01); A61K 39/39 (2006.01); A61K 39/00 (2006.01); A61K 9/00 (2006.01); A61K 9/107 (2006.01); A61K 38/08 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0005 (2013.01); A61K 9/0043 (2013.01); A61K 9/1075 (2013.01); A61K 35/74 (2013.01); A61K 38/08 (2013.01); A61K 39/39 (2013.01); A61K 47/48807 (2013.01); A61K 2039/543 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/622 (2013.01);
Abstract

The present invention provides a novel vaccine compound of micellar nanoparticles to be administered intranasally to treat and/or prevent the disease called atherosclerosis, which results from an abnormal metabolism of circulating lipids. The novelty of the vaccine compound of the present invention is the use of Archaebacterian lipids, lysophosphatidylcholine, and phosphatidylcholine, which give nanoparticles stability and facilitates antigen presentation in its appropriate secondary peptidic conformation. A novel process for the preparation of vaccine compounds which allows obtaining homogeneous nanoparticles with high stability is also presented in this invention.


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