The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9539290 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 10, 2017

Filed:

Dec. 24, 2013
Applicant:

Anticancer, Inc., San Diego, CA (US);

Inventors:

Ming Zhao, San Diego, CA (US);

Fuminari Uehara, San Diego, AZ (US);

Assignee:

AntiCancer Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/554 (2006.01); G01N 33/569 (2006.01); A61K 35/74 (2015.01); C12N 1/20 (2006.01); C12N 1/36 (2006.01);
U.S. Cl.
CPC ...
A61K 35/74 (2013.01); C12N 1/20 (2013.01); C12N 1/36 (2013.01);
Abstract

An individualized bacterial treatment of cancer is provided. The treatment includes a strain of bacteria modified by in-vivo passage through tumor grafts in experimental animals, where the modified strain exhibits enhanced cancer cell-targeting of a specific malignancy arising in a unique individual to the corresponding parent strain of bacteria. The treatment uses this modified strain for the treatment human solid-tumor malignancies by inoculating an individual with a quantity of the strain; and repeating inoculations at periodic intervals where repeated inoculations tend to progressively eliminate the solid tumor malignancy in the individual.


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