The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

Oct. 18, 2013
Applicant:

Globus Medical, Inc., Audubon, PA (US);

Inventors:

Archana Bhat, Royersford, PA (US);

Shairali Rao, Austin, TX (US);

Daniel Laskowitz, Lancaster, PA (US);

Assignee:

Globus Medical, Inc., Audubon, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61L 27/38 (2006.01); A61L 27/36 (2006.01); A61K 35/32 (2015.01); C12N 5/077 (2010.01); C12N 5/0775 (2010.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 35/32 (2013.01); A61L 27/365 (2013.01); A61L 27/3608 (2013.01); A61L 27/3834 (2013.01); A61L 27/3847 (2013.01); C12N 5/0654 (2013.01); C12N 5/0663 (2013.01); A61L 2430/02 (2013.01); C12N 2533/14 (2013.01); C12N 2533/54 (2013.01);
Abstract

Bone grafts and constructs including stem cells are provided. Example bone grafts include osteogenic stem cells seeded on a scaffold of osteoconductive cortico-cancellous chips and/or osteoinductive demineralized bone. Example constructs include extracellular matrix on a synthetic scaffold, in which the ECM is secreted from MSCs seeded onto the synthetic scaffold. Also provided are methods of making the present bone grafts and scaffolds. Further provided are methods of promoting bone healing and treating wound healing, by administering the present bone grafts and constructs to a mammal in need thereof. Also provided are kits that include the present bone grafts and/or constructs, or components thereof.


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